Article
Coexistence of TERT Promoter Mutations and the BRAF V600E Alteration and Its Impact on Histopathological Features of Papillary Thyroid Carcinoma in a Selected Series of Polish Patients.
International journal of molecular sciences - 6 Sept 2018
Rusinek Dagmara, Pfeifer Aleksandra, Krajewska Jolanta, Oczko-Wojciechowska Malgorzata, Handkiewicz-Junak Daria, Pawlaczek Agnieszka, Zebracka-Gala Jadwiga, Kowalska Malgorzata, Cyplinska Renata, Zembala-Nozynska Ewa, Chekan Mykola, Chmielik Ewa, Kropinska Aleksandra, Lamch Roman, Jurecka-Lubieniecka Beata, Jarzab Barbara, Czarniecka Agnieszka
Abstract excerpt
TERT promoter (TERTp) mutations are important factors in papillary thyroid carcinomas (PTCs). They are associated with tumor aggressiveness, recurrence, and disease-specific mortality and their use in risk stratification of PTC patients has been proposed. In this study we investigated the prevalence of TERTp mutations in a cohort of Polish patients with PTCs and the association of these mutations with...
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