Article
Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis.
Gastroenterology - 1 May 2013
Hoshida Yujin, Villanueva Augusto, Sangiovanni Angelo, Sole Manel, Hur Chin, Andersson Karin L, Chung Raymond T, Gould Joshua, Kojima Kensuke, Gupta Supriya, Taylor Bradley, Crenshaw Andrew, Gabriel Stacey, Minguez Beatriz, Iavarone Massimo, Friedman Scott L, Colombo Massimo, Llovet Josep M, Golub Todd R
Abstract excerpt
BACKGROUND & AIMS: Cirrhosis affects 1% to 2% of the world population and is the major risk factor for hepatocellular carcinoma (HCC). Hepatitis C cirrhosis-related HCC is the most rapidly increasing cause of cancer death in the United States. Noninvasive methods have been developed to identify patients with asymptomatic early-stage cirrhosis, increasing the burden of HCC surveillance, but biomarkers are needed...
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