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Article

Adipose-derived stem cell exosomes alleviate pathology of amyotrophic lateral sclerosis in vitro.

Biochemical and biophysical research communications - 21 Oct 2016

Lee Mijung, Ban Jae-Jun, Kim Ki Yoon, Jeon Gye Sun, Im Wooseok, Sung Jung-Joon, Kim Manho

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a degenerative disorder that involves the death of motor neurons in the cortex, brain stem, and spinal cord. Adipose-derived stem cells (ADSCs) are considered as a perspective remedy for therapy of neurodegenerative diseases including ALS. Stem cells secrete various factors which can modulate a hostile environment, called paracrine effect. Exosomes are small extracellular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27641665
DOI: 10.1016/j.bbrc.2016.09.069

Genes

PGC
SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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