Article
Mesenchymal stem cells alter macrophage immune responses to Leishmania major infection in both susceptible and resistance mice.
Immunology letters - 1 Feb 2016
Dameshghi Safura, Zavaran-Hosseini Ahmad, Soudi Sara, Shirazi Fatemeh Jalali, Nojehdehi Shahrzad, Hashemi Seyed Mahmoud
Abstract excerpt
Mesenchymal stem cells (MSCs) are attracted to inflammation site and switch immune system to modulate inflammatory responses. This ability makes MSCs the best candidate cells for stem cell therapy of infection diseases. Therefore, we aimed to evaluate the modulatory effect of adipose-derived MSCs (AD-MSCs) on macrophages in Leishmania (L.) major infection. Macrophages and MSCs were isolated from both susceptible...
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