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Article

Enhancement of autophagy is a potential modality for tumors refractory to radiotherapy

30 Jun 2011

Abstract excerpt

Radiotherapy is a well-established treatment for cancer. However, the existence of radioresistant cells is one of the major obstacles in radiotherapy. In order to understand the mechanism of cellular radioresistance and develop more effective radiotherapy, we have established clinically relevant radioresistant (CRR) cell lines, which continue to proliferate under daily exposure to 2 Gray (Gy) of X-rays for >30...

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PMID: 21716292
DOI: 10.1038/cddis.2011.56

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