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Article

Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 2016

McNamara Anne V, Adamson Antony D, Dunham Lee S S, Semprini Sabrina, Spiller David G, McNeilly Alan S, Mullins John J, Davis Julian R E, White Michael R H

Abstract excerpt

The use of bacterial artificial chromosome (BAC) reporter constructs in molecular physiology enables the inclusion of large sections of flanking DNA, likely to contain regulatory elements and enhancers regions that contribute to the transcriptional output of a gene. Using BAC recombineering, we have manipulated a 160-kb human prolactin luciferase (hPRL-Luc) BAC construct and mutated the previously defined...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26691151
DOI: 10.1210/me.2015-1186
PMCID: PMC4792233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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