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Neuromuscular junction degeneration in muscle wasting

1 Feb 2016

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PURPOSE OF REVIEW: Denervation is a hallmark of age-related and other types of muscle wasting. This review focuses on recent insights and current viewpoints regarding the mechanisms and clinical relevance of maintaining the neuromuscular junction to counteract muscle wasting resulting from aging or neural disease/damage. RECENT FINDINGS: Activity-dependent regulation of autophagy, the agrin-muscle specific...

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PMID: 26870889
DOI: 10.1097/mco.0000000000000267

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