Article
Variants in the interleukin-1 alpha and beta genes, and the risk for periodontal disease in dogs.
Journal of genetics - 1 Dec 2015
Albuquerque C, Morinha F, Magalhães J, Requicha J, Dias I, Guedes-Pinto H, Bastos E, Viegas C
Abstract excerpt
Elevated levels of interleukin-1 (IL-1) have been shown to amplify the inflammatory response against periodontopathogenic bacteria.In humans,polymorphisms in the IL1A and IL1B genes are the most well-studied genetic polymorphisms associated with periodontal disease (PD). In contrast to human, there is a lack of knowledge on the genetic basis of canine PD. A case-control study was conducted in which a molecular...
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