Article
Analysis of candidate susceptibility genes in canine diabetes.
The Journal of heredity - 1 Jan 2007
Short Andrea D, Catchpole Brian, Kennedy Lorna J, Barnes Annette, Fretwell Neale, Jones Chris, Thomson Wendy, Ollier William E R
Abstract excerpt
Canine diabetes is a complex genetic disease of unknown aetiology. It affects 0.005-1.5% of the canine population and shows a clear breed predisposition with the Samoyed being at high risk and the Boxer being at low risk of developing the disease. Canine diabetes is considered to be a disease homologue for human type 1 diabetes (T1D). It results in insulin deficiency as a consequence of autoimmune destruction of...
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