Article
Regulation of mitogen-activated protein kinase 3/1 activity during meiosis resumption in mammals.
The Journal of reproduction and development - 1 Jan 2015
Prochazka Radek, Blaha Milan
Abstract excerpt
In vivo, resumption of oocyte meiosis occurs in large ovarian follicles after the preovulatory surge of luteinizing hormone (LH). The LH surge leads to the activation of a broad signaling network in mural granulosa cells equipped with LH receptors. The signals generated in the mural granulosa cells are further augmented by locally produced peptides or steroids and transferred to the cumulus cell compartment and...
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