Article
Recent insights into oocyte–follicle cell interactions provide opportunities for the development of new approaches to in vitro maturation
7 Dec 2010
Abstract excerpt
The last 5-10 years of research in ovarian and oocyte biology has delivered some major new advances in knowledge of the molecular and cellular processes regulating oocyte maturation and oocyte developmental competence. These new insights include, among others: (1) the knowledge that oocytes regulate granulosa and cumulus cell differentiation, ovulation rate and fertility via the secretion of soluble paracrine...
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