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Article

Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies.

European journal of clinical pharmacology - 1 Apr 2016

Trompet S, Postmus I, Slagboom P E, Heijmans B T, Smit R A J, Maier A B, Buckley B M, Sattar N, Stott D J, Ford I, Westendorp R G J, de Craen A J M, Jukema J W

Abstract excerpt

PURPOSE: In pharmacogenetic research, genetic variation in non-responders and high responders is compared with the aim to identify the genetic loci responsible for this variation in response. However, an important question is whether the non-responders are truly biologically non-responsive or actually non-adherent? Therefore, the aim of this study was to describe, within the PROspective Study of Pravastatin in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26686871
DOI: 10.1007/s00228-015-1994-9
PMCID: PMC4792342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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