Article
Assessment of glutathione peroxidase-1 polymorphisms, oxidative stress and DNA damage in sensitivity-related illnesses.
Life sciences - 15 Jan 2016
Gugliandolo Agnese, Gangemi Chiara, Calabrò Carlo, Vecchio Mercurio, Di Mauro Debora, Renis Marcella, Ientile Riccardo, Currò Monica, Caccamo Daniela
Abstract excerpt
AIMS: Oxidative stress increase is a key event for development of sensitivity-related illnesses (SRIs). The aim of this work was to evaluate the influence of a genetic variant in the antioxidant enzyme glutathione peroxidase (GPx1) on oxidative stress development in SRIs. MAIN METHODS: GPx1 rs1800668 genotype, as well as glutathione, ubiquinone, and DNA damage were assessed in 34 SRI patients and 36 healthy...
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