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Article

Genetic testing in a cohort of young patients with HER2-amplified breast cancer.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Mar 2016

Eccles D M, Li N, Handwerker R, Maishman T, Copson E R, Durcan L T, Gerty S M, Jones L, Evans D G, Haywood L, Campbell I

Abstract excerpt

BACKGROUND: Young age at diagnosis for breast cancer raises the question of genetic susceptibility. We explored breast cancer susceptibility genes testing on ≤40-year-old patients with HER2-amplified invasive breast cancer. PATIENTS AND METHODS: Patients were selected from a large UK cohort study. The inclusion criterion was age ≤40 at diagnosis with confirmed HER2-amplified breast cancer. The probability of...

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PMID: 26681682
DOI: 10.1093/annonc/mdv592

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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