Article
Targeting MET Receptor in Rhabdomyosarcoma: Rationale and Progress
21 Jan 2016
Abstract excerpt
MET is a tyrosine kinase receptor, which binds hepatocyte growth factor (HGF). It regulates many physiological processes and participates in the regulation of proliferation, differentiation and motility of various cells. It plays an important role in embryogenesis as well as in adult life. Aberrations within the regulatory pathways activated by MET can be one of the causes of tumor development. Recently novel...
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