Article
Pathway-Based Genome-Wide Association Studies for Two Meat Production Traits in Simmental Cattle.
Scientific reports - 17 Dec 2015
Fan Huizhong, Wu Yang, Zhou Xiaojing, Xia Jiangwei, Zhang Wengang, Song Yuxin, Liu Fei, Chen Yan, Zhang Lupei, Gao Xue, Gao Huijiang, Li Junya
Abstract excerpt
Most single nucleotide polymorphisms (SNPs) detected by genome-wide association studies (GWAS), explain only a small fraction of phenotypic variation. Pathway-based GWAS were proposed to improve the proportion of genes for some human complex traits that could be explained by enriching a mass of SNPs within genetic groups. However, few attempts have been made to describe the quantitative traits in domestic...
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