Article
Genome Wide Association Studies with Different Weighting Approaches Reveals Genomic Windows Associated with Meat Quality Traits in Beef Cattle.
Genes - 28 Mar 2026
Dos Reis Hugo Borges, Maiorano Amanda Marchi, Oliveira Elisângela, Tonetto Filippi, Baldi Fernando, Fragomeni Breno de Oliveira, Ferraz José Bento Sterman
Abstract excerpt
Background/Objectives: Genome-wide association studies (GWAS) based on single-step genomic BLUP (ssGBLUP) commonly assume equal single nucleotide polymorphism (SNP) variances, which may not reflect the biological architecture of complex traits. Alternative weighting strategies can increase detection power but may affect stability. This study evaluated how different SNP weighting approaches influence genomic...
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