Article
Temperate phages acquire DNA from defective prophages by relaxed homologous recombination: the role of Rad52-like recombinases.
PLoS genetics - 1 Mar 2014
De Paepe Marianne, Hutinet Geoffrey, Son Olivier, Amarir-Bouhram Jihane, Schbath Sophie, Petit Marie-Agnès
Abstract excerpt
Bacteriophages (or phages) dominate the biosphere both numerically and in terms of genetic diversity. In particular, genomic comparisons suggest a remarkable level of horizontal gene transfer among temperate phages, favoring a high evolution rate. Molecular mechanisms of this pervasive mosaicism are mostly unknown. One hypothesis is that phage encoded recombinases are key players in these horizontal transfers,...
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