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Article

Transfer activation of SXT/R391 integrative and conjugative elements: unraveling the SetCD regulon.

Nucleic acids research - 27 Feb 2015

Poulin-Laprade Dominic, Matteau Dominick, Jacques Pierre-Étienne, Rodrigue Sébastien, Burrus Vincent

Abstract excerpt

Integrative and conjugative elements (ICEs) of the SXT/R391 family have been recognized as key drivers of antibiotic resistance dissemination in the seventh-pandemic lineage of Vibrio cholerae. SXT/R391 ICEs propagate by conjugation and integrate site-specifically into the chromosome of a wide range of environmental and clinical Gammaproteobacteria. SXT/R391 ICEs bear setC and setD, two conserved genes coding for...

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Identifiers

PMID: 25662215
DOI: 10.1093/nar/gkv071
PMCID: PMC4344509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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