Article
Single-Nucleotide Polymorphism to Associate Cancer Risk.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Shaw Victoria, Bullock Katie, Greenhalf William
Abstract excerpt
Genetic heterogeneity explains variation in predisposition for cancer. Whole-genome analysis allows risk to be quantified, giving better targeted screening and quantification of the personalized risk posed by environmental factors. Array-based approaches to whole-genome analysis are rapidly being overtaken by next-generation sequencing (NGS). In this review the different platforms currently available for NGS are...
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