Article
A Systematic Literature Review of Whole Exome and Genome Sequencing Population Studies of Genetic Susceptibility to Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2020
Rotunno Melissa, Barajas Rolando, Clyne Mindy, Hoover Elise, Simonds Naoko I, Lam Tram Kim, Mechanic Leah E, Goldstein Alisa M, Gillanders Elizabeth M
Abstract excerpt
The application of next-generation sequencing (NGS) technologies in cancer research has accelerated the discovery of somatic mutations; however, progress in the identification of germline variation associated with cancer risk is less clear. We conducted a systematic literature review of cancer genetic susceptibility studies that used NGS technologies at an exome/genome-wide scale to obtain a fuller understanding...
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