Article
[Association of ADAMTS-1 gene polymorphisms with ischemic stroke caused by large artery atherosclerosis].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2015
Lyu Chenling, Chen Yawen, Zhu Min, Jin Xiaoping, Liu Peng, Zheng Zhou, Li Cai, Zhu Feng, Hu Xiaofei, Wang Feng, Li Weiling, Wang Wanfeng
Abstract excerpt
OBJECTIVE: To assess the association of a disintegrin and metallo-proteinase with thrombospondin type 1 motifs (ADAMTS-1) gene polymorphism and ischemic stroke caused by large artery atherosclerosis (LAA). METHODS: In total 767 patients and 506 controls were recruited. Single nucleotide polymorphisms (SNPs) rs416905 (T/C) and rs402007 (G/C) of the ADAMTS-1 gene were genotyped by polymerase chain reaction and DNA...
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