Article
Prognostic relevance of lactate dehydrogenase and serum S100 levels in stage IV melanoma with known BRAF mutation status.
The British journal of dermatology - 1 Apr 2016
Frauchiger A L, Mangana J, Rechsteiner M, Moch H, Seifert B, Braun R P, Dummer R, Goldinger S M
Abstract excerpt
BACKGROUND: Activating mutations of BRAF provide an important treatment target in patients with melanoma. The prognostic role of several biochemical markers in relation to mutation status is not clear. OBJECTIVES: To analyse the prognostic significance of BRAF mutation in patients with melanoma and correlate it to different markers. METHODS: In total, 162 patients with stage IV melanoma and known BRAF mutation...
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