Article
Predictive Significance of Combined Plasmatic Detection of BRAF Mutations and S100B Tumor Marker in Early-Stage Malignant Melanoma.
Cancer medicine - 1 Oct 2024
Polivka Jiri, Gouda Mohamed A, Sharif Mahyar, Pesta Martin, Huang Helen, Treskova Inka, Woznica Vlastimil, Windrichova Jindra, Houfkova Katerina, Kucera Radek, Fikrle Tomas, Ricar Jan, Pivovarcikova Kristyna, Topolcan Ondrej, Janku Filip
Abstract excerpt
BACKGROUND: Melanoma is the most aggressive skin cancer with ability to recur also after early-stage tumor surgery. The aim was to identify early-stage melanoma patients at high risk of recurrence using liquid biopsy, estimating of mutated BRAF ctDNA and the level of tumor marker S100B in plasma. METHODS: Eighty patients were enrolled in the study. BRAF V600E mutation was determined in FFPE tissue and plasma...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.