Article
Genomic analysis suggests higher susceptibility of children to air pollution.
Carcinogenesis - 1 May 2008
van Leeuwen Danitsja M, Pedersen Marie, Hendriksen Peter J M, Boorsma André, van Herwijnen Marcel H M, Gottschalk Ralph W H, Kirsch-Volders Micheline, Knudsen Lisbeth E, Srám Radim J, Bajak Edyta, van Delft Joost H M, Kleinjans Jos C S
Abstract excerpt
Differences in biological responses to exposure to hazardous airborne substances between children and adults have been reported, suggesting children to be more susceptible. Aim of this study was to improve our understanding of differences in susceptibility in cancer risk associated with air pollution by comparing genome-wide gene expression profiles in peripheral blood of children and their parents. Gene...
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