Article
Deletion of GOLGA2P3Y but not GOLGA2P2Y is a risk factor for oligozoospermia.
Reproductive biomedicine online - 1 Feb 2016
Sen Sanjukta, Agarwal Rupesh, Ambulkar Prafulla, Hinduja Indira, Zaveri Kusum, Gokral Jyotsna, Pal Asoke, Modi Deepak
Abstract excerpt
The AZFc locus on the human Y chromosome harbours several multicopy genes, some of which are required for spermatogenesis. It is believed that deletion of one or more copies of these genes is a cause of infertility in some men. GOLGA2LY is one of the genes in the AZFc locus and it exists in two copies, GOLGA2P2Y and GOLGA2P3Y. The involvement of GOLGA2LY gene copy deletions in male infertility, however, is...
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