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Article

A Door Opens for Fibrodysplasia Ossificans Progressiva.

Trends in biochemical sciences - 1 Feb 2016

Katagiri Takenobu

Abstract excerpt

Fibrodysplasia ossificans progressiva (FOP), characterized by extra bone formation in soft tissues, is caused by a gain-of-function mutation in ACVR1, a transmembrane receptor. Recently, a potential treatment was developed by identifying a novel molecular mechanism underlying bone formation in FOP. These findings have opened the door to beating FOP.

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Identifiers

PMID: 26654278
DOI: 10.1016/j.tibs.2015.11.010

Genes

ACVR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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