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Article

Pro-Resolving Lipid Mediators Improve Neuronal Survival and Increase Aβ42 Phagocytosis.

Molecular neurobiology - 1 May 2016

Zhu Mingqin, Wang Xiuzhe, Hjorth Erik, Colas Romain A, Schroeder Lisa, Granholm Ann-Charlotte, Serhan Charles N, Schultzberg Marianne

Abstract excerpt

Inflammation in the brain is a prominent feature in Alzheimer's disease (AD). Recent studies suggest that chronic inflammation can be a consequence of failure to resolve the inflammation. Resolution of inflammation is mediated by a family of lipid mediators (LMs), and the levels of these specialized pro-resolving mediators (SPMs) are reduced in the hippocampus of those with AD. In the present study, we combined...

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Identifiers

PMID: 26650044
DOI: 10.1007/s12035-015-9544-0
PMCID: PMC4824659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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