Article
Macrocalcitonin Is a Novel Pitfall in the Routine of Serum Calcitonin Immunoassay.
The Journal of clinical endocrinology and metabolism - 1 Feb 2016
Alves Thalita G, Kasamatsu Teresa S, Yang Ji H, Meneghetti Maria Cecília Z, Mendes Aline, Kunii Ilda S, Lindsey Susan C, Camacho Cléber P, Dias da Silva Magnus R, Maciel Rui M B, Vieira José Gilberto H, Martins João Roberto M
Abstract excerpt
CONTEXT: Calcitonin (CT) is a sensitive marker of medullary thyroid carcinoma (MTC) and is used for primary diagnosis and follow-up after thyroidectomy. However, persistently elevated CT is observed even after complete surgical removal without evidence of a recurrent or persistent tumor. OBJECTIVE: To investigate the presence of assay interference in the serum CT of MTC patients who are apparently without a...
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