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Article

Functional advantage of educated KIR2DL1(+) natural killer cells for anti-HIV-1 antibody-dependent activation.

Clinical and experimental immunology - 1 Apr 2016

Gooneratne S L, Center R J, Kent S J, Parsons M S

Abstract excerpt

Evidence from the RV144 HIV-1 vaccine trial implicates anti-HIV-1 antibody-dependent cellular cytotoxicity (ADCC) in vaccine-conferred protection from infection. Among effector cells that mediate ADCC are natural killer (NK) cells. The ability of NK cells to be activated in an antibody-dependent manner is reliant upon several factors. In general, NK cell-mediated antibody-dependent activation is most robust in...

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Share to CD57 Antigens
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Antibodies

Share to HLA-C Antigens

Share to Immunity, Humoral

Share to Immunologic Memory

Share to Primary Cell Culture

Share to Receptors, KIR2DL1

Source

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Identifiers

PMID: 26647083
DOI: 10.1111/cei.12752
PMCID: PMC4778096

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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