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Article

The role of natural killer (NK) cells and NK cell receptor polymorphisms in the assessment of HIV-1 neutralization.

PloS one - 1 Jan 2012

Brown Bruce K, Wieczorek Lindsay, Kijak Gustavo, Lombardi Kara, Currier Jeffrey, Wesberry Maggie, Kappes John C, Ngauy Viseth, Marovich Mary, Michael Nelson, Ochsenbauer Christina, Montefiori David C, Polonis Victoria R

Abstract excerpt

The importance of innate immune cells in HIV-1 pathogenesis and protection has been highlighted by the role of natural killer (NK) cells in the containment of viral replication. Use of peripheral blood mononuclear cells (PBMC) in immunologic studies provides both HIV-1 target cells (ie. CD4+ T cells), as well as anti-HIV-1 effector cells, such as NK cells. In this study, NK and other immune cell populations were...

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Share to Antibodies, Neutralizing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Killer Cells, Natural

Share to Leukocytes, Mononuclear

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Share to Receptors, IgG

Share to Receptors, KIR3DS1

Share to Receptors, Natural Killer Cell

Source

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Identifiers

PMID: 22509241
DOI: 10.1371/journal.pone.0029454
PMCID: PMC3324450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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