Article
Nutrient deprivation-related OXPHOS/glycolysis interconversion via HIF-1α/C-MYC pathway in U251 cells.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2016
Liu Zhongjian, Sun Yang, Tan Shirui, Liu Liang, Hu Suqiong, Huo Hongyu, Li Meizhang, Cui Qinghua, Yu Min
Abstract excerpt
Although the Warburg effect is a dominant metabolic phenotype observed in cancers, the metabolic changes and adaptation occurring in tumors have been demonstrated to extend beyond the Warburg effect and thus considered a secondary effect to the transformation process of carcinogenesis, including nutritional deficiencies. However, the role of nutritional deficiencies in this metabolic reprogramming (e. g.,...
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