Article
Endothelin B receptor expression in malignant gliomas: the perivascular immune escape mechanism of gliomas.
Journal of neuro-oncology - 1 Mar 2016
Nakashima Shinji, Sugita Yasuo, Miyoshi Hiroaki, Arakawa Fumiko, Muta Hiroko, Ishibashi Yukinao, Niino Daisuke, Ohshima Koichi, Terasaki Mizuhiko, Nakamura Yukihiko, Morioka Motohiro
Abstract excerpt
In order to clarify the role of endothelin B receptors (ETBRs) in gliomas, we analyzed cell cultures and surgical specimens of gliomas using RT-PCR and immunohistochemistry. RT-PCR measured the absolute expression of ETBR mRNA in twelve samples, which included gliomas that were classified using the World Health Organization (WHO) classification system Grade I-IV, as well as two glioblastoma cell lines (CCF-STTG1...
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