Article
Thromboxane synthase regulates the migratory phenotype of human glioma cells.
Neuro-oncology - 1 Jan 1999
Giese A, Hagel C, Kim E L, Zapf S, Djawaheri J, Berens M E, Westphal M
Abstract excerpt
The capacity of glial tumor cells to migrate and diffusely infiltrate normal brain compromises surgical eradication of the disease. Identification of genes associated with invasion may offer novel strategies for anti-invasive therapies. The gene for TXsyn, an enzyme of the arachidonic acid pathway, has been identified by differential mRNA display as being overexpressed in a glioma cell line selected for...
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