Article
Evaluation of potential regulatory function of breast cancer risk locus at 6q25.1.
Carcinogenesis - 1 Feb 2016
Sun Yaqiong, Ye Chuanzhong, Guo Xingyi, Wen Wanqing, Long Jirong, Gao Yu-Tang, Shu Xiao Ou, Zheng Wei, Cai Qiuyin
Abstract excerpt
In a genome-wide association study conducted among Chinese women, we identified the single nucleotide polymorphism (SNP) rs2046210 at 6q25.1 for breast cancer risk. To explore a potential regulatory role for this risk locus, we measured expression levels of nine genes at the locus in breast cancer tissue and adjacent normal tissue samples obtained from 67 patients recruited in the Shanghai Breast Cancer Study. We...
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