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Article

Ephrin-A3 promotes and maintains slow muscle fiber identity during postnatal development and reinnervation.

The Journal of cell biology - 7 Dec 2015

Stark Danny A, Coffey Nathan J, Pancoast Hannah R, Arnold Laura L, Walker J Peyton D, Vallée Joanne, Robitaille Richard, Garcia Michael L, Cornelison D D W

Abstract excerpt

Each adult mammalian skeletal muscle has a unique complement of fast and slow myofibers, reflecting patterns established during development and reinforced via their innervation by fast and slow motor neurons. Existing data support a model of postnatal "matching" whereby predetermined myofiber type identity promotes pruning of inappropriate motor axons, but no molecular mechanism has yet been identified. We...

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Identifiers

PMID: 26644518
DOI: 10.1083/jcb.201502036
PMCID: PMC4674275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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