Genetic variation in vitamin D receptor gene (Fok1:rs2228570) is associated with risk of coronary artery disease.

doi:10.3109/1354750X.2015.1118535

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Article

Genetic variation in vitamin D receptor gene (Fok1:rs2228570) is associated with risk of coronary artery disease.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2016

Abu El Maaty Mohamed A, Hassanein Sally I, Gad Mohamed Z

Abstract excerpt

OBJECTIVE: The Fok1 polymorphism (rs2228570) in vitamin D receptor gene appears to be the only polymorphism influencing size of translated protein. Investigations into its association with coronary artery disease (CAD) are sparse. METHODS: Male patients (n = 98) with verified CAD were recruited alongside age- and sex-matched controls (n = 55). Genotyping was performed by PCR-RFLP and plasma 25-Hydroxyvitamin D...

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PMID: 26643870
DOI: 10.3109/1354750X.2015.1118535

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