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Article

The vitamin D receptor functional variant rs2228570 (C>T) does not associate with type 2 diabetes mellitus.

Endocrine research - 1 Nov 2017

Bertoccini Laura, Sentinelli Federica, Leonetti Frida, Bailetti Diego, Capoccia Danila, Cimini Flavia A, Barchetta Ilaria, Incani Michela, Lenzi Andrea, Cossu Efisio, Cavallo M Gisella, Baroni Marco G

Abstract excerpt

AIM: Vitamin D acts through the binding to the vitamin D receptor (VDR). Several polymorphisms in VDR gene have been studied. Among these, the rs2228570 C>T (FokI) variant has been demonstrated to be functional, leading to a protein with a different size and activity. So far, genetic studies on the association between VDR gene rs2228570 single nucleotide polymorphism (SNP) and type 2 diabetes mellitus (T2DM)...

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Source

Identifiers

PMID: 28388281
DOI: 10.1080/07435800.2017.1305965

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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