Article
Pharmacogenetic analysis of advanced non-small-cell lung cancer patients treated with first-line paclitaxel and carboplatin chemotherapy.
Pharmacogenetics and genomics - 1 Mar 2016
Park Hyung Soon, Lim Sun Min, Shin Ho Jung, Cho Arthur, Shin Jae-Gook, Lee Min Goo, Kim Hye Ryun, Kim Joo Hang, Cho Byoung Chul
Abstract excerpt
BACKGROUND: Genetic polymorphisms contribute toward interindividual variations in drug response. We investigated the effects of genetic polymorphisms on the clinical outcome of advanced non-small-cell lung cancer patients with first-line paclitaxel and carboplatin. MATERIALS AND METHODS: A total of 194 non-small-cell lung cancer patients were prospectively enrolled from January 2010 to January 2013. We genotyped...
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