Article
CYP2C19 drug-drug and drug-gene interactions in ED patients.
The American journal of emergency medicine - 1 Feb 2016
Flaten Hanna K, Kim Howard S, Campbell Jenny, Hamilton Lisa, Monte Andrew A
Abstract excerpt
BACKGROUND: CYP450 polymorphisms result in variable rates of drug metabolism. CYP drug-drug interactions can contribute to altered drug effectiveness and safety. STUDY OBJECTIVES: The primary objective was to determine the percentage of emergency department (ED) patients with cytochrome 2C19 (CYP2C19) drug-drug interactions. The secondary objective was to determine the prevalence of CYP2C19 polymorphisms in a US...
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