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Article

Association between high expression macrophage migration inhibitory factor (MIF) alleles and West Nile virus encephalitis.

Cytokine - 1 Feb 2016

Das Rituparna, Loughran Kerry, Murchison Charles, Qian Feng, Leng Lin, Song Yan, Montgomery Ruth R, Loeb Mark, Bucala Richard

Abstract excerpt

Infection with mosquito-borne West Nile virus (WNV) is usually asymptomatic but can lead to severe WNV encephalitis. The innate cytokine, macrophage migration inhibitory factor (MIF), is elevated in patients with WNV encephalitis and promotes viral neuroinvasion and mortality in animal models. In a case-control study, we examined functional polymorphisms in the MIF locus in a cohort of 454 North American patients...

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Identifiers

PMID: 26638028
DOI: 10.1016/j.cyto.2015.11.021
PMCID: PMC4696904

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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