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Article

MIF, MIF alleles, and prospects for therapeutic intervention in autoimmunity.

Journal of clinical immunology - 1 Jan 2013

Bucala Richard

Abstract excerpt

Macrophage migration inhibitory factor (MIF) is an innate cytokine whose main actions include counter-regulating the immunosuppressive action of glucocorticoids and inhibiting activation-induced apoptosis. MIF is encoded in a functionally polymorphic locus and human genetic studies have shown significant relationships between high-expression MIF alleles, host inflammatory responses, and improved clinical outcome...

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Topics

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Share to Alleles
Share to Antibodies, Monoclonal
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MIF gene

Share to Lupus Erythematosus, Systemic

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Share to Receptors, Immunologic

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Source

Open in PubMed Open full text

Identifiers

PMID: 22968741
DOI: 10.1007/s10875-012-9781-1
PMCID: PMC3548018

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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