Article
Investigating Olfactory Gene Variation and Odour Identification in Older Adults.
Genes - 29 Apr 2021
Raj Siddharth, Thalamuthu Anbupalam, Armstrong Nicola J, Wright Margaret J, Kwok John B, Trollor Julian N, Ames David, Schofield Peter R, Brodaty Henry, Sachdev Perminder S, Mather Karen A
Abstract excerpt
Ageing is associated with a decrease in odour identification. Additionally, deficits in olfaction have been linked to age-related disease and mortality. Heritability studies suggest genetic variation contributes to olfactory identification. The olfactory receptor (OR) gene family is the largest in the human genome and responsible for overall odour identification. In this study, we sought to find olfactory gene...
Topics
- Aged
- Aged, 80 and over
- Aging
- Female
- Humans
- Male
- Olfactory Perception
- Polymorphism, Single Nucleotide
- Receptors, Odorant
- Smell