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Inverse birth cohort effects in ovarian cancer: Increasing risk in BRCA1/2 mutation carriers and decreasing risk in the general population.

Gynecologic oncology - 1 Feb 2016

Vos Janet R, Mourits Marian J, Teixeira Natalia, Jansen Liesbeth, Oosterwijk Jan C, de Bock Geertruida H

Abstract excerpt

OBJECTIVE: BRCA1/2 carriers are at increased risk of ovarian cancer, and some reports suggest an increasing risk in more recent birth cohorts. In contrast, decreasing incidences have been observed in the general population. The aim was to assess the birth cohort effect on ovarian cancer risk in BRCA1/2 carriers relative to their background general population. METHODS: Data on ovarian cancer incidence was...

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Source

Identifiers

PMID: 26631606
DOI: 10.1016/j.ygyno.2015.11.029

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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