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Article

Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes

25 Nov 2015

Abstract excerpt

Stem cell-derived somatic cells represent an unlimited resource for basic and translational science. Although promising, there are significant hurdles that must be overcome. Our focus is on the generation of the major cell type of the human liver, the hepatocyte. Current protocols produce variable populations of hepatocytes that are the product of using undefined components in the differentiation process. This...

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PMID: 26626180
DOI: 10.1016/j.stemcr.2015.10.016

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