Article
Biotechnology Challenges to In Vitro Maturation of Hepatic Stem Cells.
Gastroenterology - 1 Apr 2018
Chen Chen, Soto-Gutierrez Alejandro, Baptista Pedro M, Spee Bart
Abstract excerpt
The incidence of liver disease is increasing globally. The only curative therapy for severe end-stage liver disease, liver transplantation, is limited by the shortage of organ donors. In vitro models of liver physiology have been developed and new technologies and approaches are progressing rapidly. Stem cells might be used as a source of liver tissue for development of models, therapies, and tissue-engineering...
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