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Article

Engineering and expression of a human rotavirus candidate vaccine in Nicotiana benthamiana.

Virology journal - 2 Dec 2015

Pêra Francisco F P G, Mutepfa David L R, Khan Ayesha M, Els Johann H, Mbewana Sandiswa, van Dijk Alberdina A A, Rybicki Edward P, Hitzeroth Inga I

Abstract excerpt

BACKGROUND: Human rotaviruses are the main cause of severe gastroenteritis in children and are responsible for over 500 000 deaths annually. There are two live rotavirus vaccines currently available, one based on human rotavirus serotype G1P[8], and the other a G1-G4 P[8] pentavalent vaccine. However, the recent emergence of the G9 and other novel rotavirus serotypes in Africa and Asia has prompted fears that...

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Source

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Identifiers

PMID: 26626122
DOI: 10.1186/s12985-015-0436-8
PMCID: PMC4667453

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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