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Article

Super-enhancer lncs to cardiovascular development and disease.

Biochimica et biophysica acta - 1 Jul 2016

Ounzain Samir, Pedrazzini Thierry

Abstract excerpt

Cardiac development, function and pathological remodelling in response to stress depend on the dynamic control of tissue specific gene expression by distant acting transcriptional enhancers. Recently, super-enhancers (SEs), also known as stretch or large enhancer clusters, are emerging as sentinel regulators within the gene regulatory networks that underpin cellular functions. It is becoming increasingly evident...

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Share to Cardiovascular Diseases
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Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

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Share to RNA, Long Noncoding

Source

Identifiers

PMID: 26620798
DOI: 10.1016/j.bbamcr.2015.11.026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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