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Article

Type I IFNs induce anti-tumor polarization of tumor associated neutrophils in mice and human.

International journal of cancer - 15 Apr 2016

Andzinski Lisa, Kasnitz Nadine, Stahnke Stephanie, Wu Ching-Fang, Gereke Marcus, von Köckritz-Blickwede Maren, Schilling Bastian, Brandau Sven, Weiss Siegfried, Jablonska Jadwiga

Abstract excerpt

The importance of tumor associated neutrophils (TANs) in cancer development is in the meantime well established. Numerous of clinical data document the adverse prognostic effects of neutrophil infiltration in solid tumors. However, certain tumor therapies need functional neutrophils to be effective, suggesting altered neutrophil polarization associated with different outcomes for cancer patients. Therefore,...

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Source

Identifiers

PMID: 26619320
DOI: 10.1002/ijc.29945

Genes

ICAM1
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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