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Article

Impact of EGFR mutations and KRAS amino acid substitution on the response to radiotherapy for brain metastasis of non-small-cell lung cancer.

Future oncology (London, England) - 1 Jan 2016

Renaud Stéphane, Schaeffer Mickaël, Voegeli Anne-Claire, Legrain Michèle, Guérin Eric, Meyer Nicolas, Mennecier Bertrand, Quoix Elisabeth, Falcoz Pierre-Emmanuel, Guénot Dominique, Massard Gilbert, Noël Georges, Beau-Faller Michèle

Abstract excerpt

BACKGROUND: Our study aimed to evaluate response rate (RR) to brain metastasis radiotherapy (RT), depending on the genomic status of non-small-cell lung cancer. MATERIAL & METHODS: We retrospectively reviewed 1971 non-small-cell lung cancer files of patients with EGFR and KRAS testing and focused on 157 patients who had undergone RT for brain metastasis. RESULTS: A total of 16 patients (10.2%) harbored EGFR...

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Identifiers

PMID: 26616848
DOI: 10.2217/fon.15.273

Genes

EGFR
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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